| Ellie Church | as | Sarah | |
 | Debbie Rochon | as | Leslie |
| Charlie Moon | as | Lailah |
 | Richard Cabral | as | Arturo |
 | Carlos Pratts | as | Oscar Hernandez |
| Eddie J. Fernandez | as | Carlos | |
| Jorge Diaz | as | Hector | |
| David Fernandez Jr. | as | Cholo | |
 | Molly Ephraim | as | Ali |
 | Katie Featherston | as | Katie |
| Andrew Jacobson | as | Jesse | |
| Crystal Santos | as | Santos | |
| Catherine Toribio | as | Penelope |
 | Elijah Wood | as | |
 | Alison Pill | as | |
 | Rainn Wilson | as | |
 | Jack McBrayer | as | |
 | Nasim Pedrad | as | |
 | Leigh Whannell | as | |
 | Jorge Garcia | as | Rick |
 | Marlon Wayans | as | Malcolm |
 | Jaime Pressly | as | Megan |
 | Essence Atkins | as | Kisha |
 | Gabriel Iglesias | as | Miguel |
 | Missi Pyle | as | Noreen |
 | Ashley Rickards | as | Becky |
 | Affion Crockett | as | Ray- Ray |
| Steele Stebbins | as | Wyatt | |
 | Rick Overton | as | Professor Wilde |
 | Dave Sheridan | as | Agouhl |
 | Cedric the Entertainer | as | Father Doug |
| Audrey Petenbrink | as | Pool Daughter (uncredited) | |
| Scott Burn | as | Kill Family Dad (uncredited) |
 | Jamie Chung | as | |
 | Nicky Whelan | as | |
 | Leslie Bibb | as | |
 | Amy Smart | as | |
 | Scout Taylor-Compton | as | |
 | Ryan Kwanten | as | |
 | Johnathon Schaech | as | Pilot |
 | Christian Serratos | as | |
 | Jerry Ferrara | as | |
 | Alex Frost | as |
| Brooke Anne Smith | as | Kaylie | |
 | Malcolm McDowell | as | Mr. Smiles |
| Michael Taylor | as | ||
 | Ramon Tikaram | as | |
 | Holly Kenny | as |
| Katherine Sigimund | as | Katie Morris | |
| Corey Eid | as | Corey Morris | |
 | Riley Polanski | as | Riley Morris |
| Jillian Clare | as | Jillian Morris | |
| Jeff Bowser | as | Sean | |
| Peter Holden | as | Peter Morris | |
| Walter Phelan | as | ||
| Jordan Turchin | as | Officer James | |
| Kelley Hinman | as | Park Ranger | |
| Ben Sharples | as |
 | Annabelle Wallis | as | |
| Ward Horton | as |